Heparin-binding EGF-like Growth Factor

An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.

Also Known As:

HB-EGF; Diphtheria Toxin Receptor; Diphtheria Toxin Receptors; HB-EGF Precursor; Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein; Receptor, Diphtheria Toxin; SF HB-EGF; Short Form HB-EGF; HB EGF; HB EGF Precursor; HB-EGF, Short Form; Heparin binding EGF like Growth Factor; Heparin binding Epidermal Growth Factor like Growth Factor Precursor Protein; Receptors, Diphtheria Toxin; SF HB EGF; Short Form HB EGF; Toxin Receptor, Diphtheria; Toxin Receptors, Diphtheria; Heparin-binding EGF-like Growth-Factor

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - EGF Family of Proteins: 90
      - Heparin-binding EGF-like Growth Factor: 699
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - EGF Family of Proteins: 90
      - Heparin-binding EGF-like Growth Factor: 699
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - EGF Family of Proteins: 90
    - Heparin-binding EGF-like Growth Factor: 699

Estelle Oertling Selected Research

Estelle Oertling Research Topics

Disease

Drug/Important Bio-Agent (IBA)